[RC Como] EPIDEMIOLOGIA GENETICA

Dottor Tommaso Dragani – Epidemiologo e Scienziato

Tommaso A. Dragani is an Italian genetic epidemiologist whose research is focused on understanding the genetic control of complex phenotypes.[1][2][3][4][5][6]

Results from his studies allowed the chromosomal mapping of quantitative trait loci (QTLs) modulating the genetic predisposition to liver, lung and skin tumorigenesis, in animal models.[7][8][9][10][11][12] His population-based studies resulted in the identification of genetic polymorphisms associated with the risk and prognosis of lung cancer. He contributed to discovering the mechanism underlying the association between polymorphisms in nicotinic acetylcholine receptor subunit genes on chromosome 15 and the risks of lung cancer and nicotine dependence.[13][14] He contributed with a genome-wide study to the pharmacogenomics of pain relief in response to opioid therapy for cancer pain.[15]

Biography[edit]

Dragani was born in Ortona, Italy, and studied pharmacy at the University of Bologna where he received and MPharm degree in 1977. He then joined the National Cancer Institute in Milan [it] as a researcher.

From June 1984 to June 1985, he was visiting scientist at the laboratory of Bernard Weinstein, Columbia University, and from September 1996 to February 1997 he was visiting scientist at the National Cancer Center Japan [jp], working with Minako Nagao.

In 1998, Dragani was appointed Director of the Genetic Epidemiology and Pharmacogenomics Research Unit at the National Cancer Institute in Milan. In 2007 he achieved a Masters in Medical Statistics and Statistical Methods in Epidemiology by the University of Milan.

Il dott. Dragani  è direttore dell'Unità di Ricerca di Epidemiologia Genetica e Farmacogenomica presso la Fondazione IRCCS Istituto Nazionale dei Tumori in Italia. È stato un pioniere della ricerca sulla predisposizione genetica al cancro.

Informazioni ed iscrizioni a: segreteria@rotarycomo.it

Foto di National Cancer Institute su unsplash.com